Clinical research

Alluvial diagram example: disease severity over 12 months

Example alluvial diagram of patients moving between severity levels at baseline, month 6 and month 12, including dropouts. Open it in the editor and replace the data with your own.

Open this example in the editorStart from scratch

Severe (69)Moderate (90)Mild (64)Severe (25)Severe (25)Moderate (61)Moderate (61)Mild (80)Mild (80)Dropped out (21)Dropped out (21)Remission (36)Remission (36)Severe (25)Moderate (42)Mild (69)Remission (66)Dropped out (21)BaselineMonth 6Month 12
Patients by disease severity at three time points; flows are colored by baseline severity. Illustrative data.

About this example

Longitudinal clinical studies often report how many patients improve, stay the same or worsen between visits. A table of transition counts is hard to read; an alluvial diagram shows the same numbers as flows, so readers can follow each baseline group through follow-up.

Coloring the flows by baseline severity keeps each group traceable across stages. Showing dropouts as their own category makes attrition visible instead of silently removing those patients, which reviewers usually ask for.

The data

BaselineMonth 6Month 12Patients
SevereSevereSevere18
SevereModerateModerate22
SevereModerateMild14
SevereMildRemission6
SevereDropped outDropped out9
ModerateModerateModerate20
ModerateMildMild31
ModerateMildRemission24
ModerateSevereSevere7
ModerateDropped outDropped out8
MildMildMild19
MildRemissionRemission36
MildModerateMild5
MildDropped outDropped out4

Open the example, replace the data with your own, and export the figure as SVG, PDF or a 600 dpi PNG.

More examples